Effect of autophagy in human tongue squamous cell carcinoma SCC 25 cells from Scutellariae Radix by ethanol extract
نویسندگان
چکیده
منابع مشابه
Tongue Squamous Cell Carcinoma: A Clinical Study
Background and Objectives: Squamous cell carcinoma of the tongue (SCCOT) is the most common malignant neoplasm in oral cavity. At the time of the diagnosis of SCCOT regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. Although the level of healthcare has significantly improved, the survival rate is still low with an...
متن کاملThe Prevalence of Human Papilloma Virus in Squamous Cell Carcinoma of Oral Tongue
Background and objective: Oral tongue Squamous Cell carcinoma (SCC) commonly involves males between the sixth to eighth decades of life. Major risk factors are tobacco usage and alcohol consumption. The increasing number of patients developing oral tongue cancer without these well-known risk factors suggests that a viral infection, such as Human Papil...
متن کاملEffect of HIF-1α on biological activation of human tongue squamous cell carcinoma SCC-15 cells in vitro
Hypoxia-inducible factor-1α (HIF-1α) is a key regulator for tumor cells and tissues to adapt to hypoxic condition. Suppressing the expression of HIF-1α is important to evaluate its effect on cancer cells. This study was carried out to analyze the effect of HIF-1α on the biological activation of human tongue squamous cell carcinoma (TSCC) SCC-15 cells. In this experiment, deferoxamine mesylate (...
متن کاملANO1 as a marker of oral squamous cell carcinoma and silencing ANO1 suppresses migration of human scc-25 cells
OBJECTIVES The purpose of this study is to confirm that ANO1 correlates with occurrence and metastasis of OSCC. STUDY DESIGN Immunohistochemistry was used to detect the expression of ANO1 in 160 specimens of OSCC and normal tissues. Lentiviral silencing ANO1 was used in SCC-25 cell line to study the cell migration and cell detachment. RESULTS Immunohistochemical staining revealed that ANO1 ...
متن کاملSerum Level of Interleukin-6 in Patients with Oral Tongue Squamous cell Carcinoma
Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to investigate the serum le...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Korean society of Dental Hygiene
سال: 2014
ISSN: 2287-1705
DOI: 10.13065/jksdh.2014.14.02.287